Deutsch: Trilostan / Español: Trilostano / Português: Trilostano / Français: Trilostane / Italiano: Trilostano /
Trilostane is a pharmaceutical compound used in the industrial and veterinary context. It is classified as a competitive inhibitor of the enzyme 3-beta-hydroxysteroid dehydrogenase and is primarily employed to manage certain medical conditions in animals. Trilostane is particularly known for its role in the treatment of Cushing's syndrome, a hormonal disorder that affects both humans and animals.
Application Areas:
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Veterinary Medicine: Trilostane is primarily used in veterinary medicine to treat Cushing's syndrome in dogs, a condition characterized by excessive cortisol production. It helps regulate cortisol levels and alleviate symptoms such as excessive thirst, urination, and skin issues in affected animals.
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Pharmaceutical Industry: Trilostane serves as an active pharmaceutical ingredient (API) in the formulation of medications designed to manage Cushing's syndrome in dogs and other animals.
Well-Known Examples:
- Vetoryl: Vetoryl is a widely recognized veterinary medication containing trilostane as its active ingredient. It is prescribed by veterinarians for the treatment of Cushing's syndrome in dogs.
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Side Effects: Trilostane can lead to various side effects in animals, including gastrointestinal issues, lethargy, and changes in electrolyte levels. Close monitoring by veterinarians is necessary during treatment.
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Dosing Accuracy: Ensuring the correct dosage of trilostane is crucial, as improper dosing can lead to over- or under-treatment of Cushing's syndrome.
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Adverse Reactions: Some animals may experience adverse reactions or allergies to trilostane, necessitating discontinuation of treatment.
Recommendations: The use of trilostane in veterinary medicine should be closely supervised by trained veterinarians who can accurately diagnose and manage Cushing's syndrome in animals. Proper dosage and monitoring are essential to minimize side effects and ensure the effectiveness of treatment.
History and Legal Basics: Trilostane was developed and approved for use in veterinary medicine to address Cushing's syndrome in dogs. The legal and regulatory aspects of trilostane's use in veterinary medicine are subject to the respective regulations and guidelines of individual countries and regions.
Examples of Sentences:
- Trilostane has proven effective in managing Cushing's syndrome in dogs.
- The dosage of trilostane's active ingredient must be carefully determined.
- Many veterinarians prescribe medications containing trilostane to treat Cushing's syndrome in animals.
- The veterinarian is currently trilostane-ing the dog to control cortisol levels.
Similar Things or Synonyms:
- Cushing's syndrome treatment
- Veterinary medication for hyperadrenocorticism
- Competitive enzyme inhibitor for cortisol regulation
Summary: Trilostane is a pharmaceutical compound used in veterinary medicine for the treatment of Cushing's syndrome in dogs and other animals. It acts as a competitive inhibitor of the enzyme 3-beta-hydroxysteroid dehydrogenase, helping to regulate cortisol levels and alleviate symptoms associated with the disorder. Proper diagnosis, dosage, and monitoring by veterinarians are essential to ensure the safe and effective use of trilostane in managing Cushing's syndrome in animals.
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