The term sofa or SOFA may refer to the following:
- sofa (also couch, settee, chesterfield, divan, davenport, lounge, canapé) a piece of furniture that seats two or more people in the form of a bench, and has a backrest
- SOFA (Simulation Open Framework Architecture), an open source computer physics engine
- SOFA (Standards of Fundamental Astronomy), a set of software libraries, available for both C and Fortran, for use in astronomy-related computations
- SOFA (Sequential Organ Failure Assessment) score, a scoring system used to keep track of an ICU patient's status during their stay at the ICU
- SOFA 2, a component system and/or framework for developing component-based applications
- Statement of financial affairs, a type of document required in US law for declaring bankruptcy
- Status of forces agreement, an agreement between a host country and a foreign nation stationing military forces in that country
- a short-lived Canadian band
- a song from from American musicians Frank Zappa and The Mothers of Invention's 1975 album, One Size Fits All