The acronym DME may refer to the following:

  • Diastatic Malt Extract, a type of ingredient used in homebrewing (of beer)
  • Dimethyl ether (or methoxymethane), a colorless, gaseous ether
  • Dimethyoxethane (also glyme, monoglyme, dimethyl alcohol, ethylene glycol dimethyl ether, dimethyl cellosolve, DME), a type of clear, colorless, liquid ether that can be mixed with water, and is used as a solvent
  • Diabetic Macular Edema, a type of ocular disease, specifically as a complication of diabetes
  • Digital Multi Effects, a type of device used for video image manipulation, such as in live broadcasting and post-production
  • Distance Measuring Equipment, a transponder-based radio navigation technology used by aircraft for determining distance